MSc Bioinformatics students Sucharitha Balu, Kieran Drake, Kyvi
Nguyen, Vuyelwa Nkomo
and Ruchira Sachdeva have joined the group to do their projects on
B-cell germline genes, T-cell receptors, and SARS-CoV-2.
Adrian Shepherd is giving a talk about the group's computational
immunology research at the Royal Veterinary College on the
Congratulations to Lenka Stejkal and other group members for having a
paper on the hepatitis C virus E2 glycoprotein published
Sarah Griffiths joins the group to do an internship aimed at
different antibody repertoire annotation tools.
Adrian Shepherd is giving a talk on alloimmunity and our proteome
scanning strategy at
and Tolerance Seminar in Amsterdam on the 15th. Three members of the group are co-authors on a paper
in Frontiers in
Immunology abouta statistical package for analysing and
comparing immune receptor repertoires called sumrep.
Zainab Aziz and Trupti Gore join the group to do internships on MHC
molecule binding signatures and HLA allele prediction from T-cell receptor
Congratulations to Dr William Lees for having two papers accepted in
Nucleic Acids Research — one for our
database OGRDB, and
one for VDJbase, which we
host and jointly develop with Gur Yaari's lab.
Adrian Shepherd is giving a talk about antibody repertoire sequencing
Engineering & Therapeutics Europe
conference in Amsterdam on the 13th.
MSc Bioinformatics students Esther Adebanjo, Sam Dougan, Diego, Miruna
Serian and Nikita Sharma join the group to do their Masters projects.
Congratulations to William Lees for having
on inferred allelic variants of immunoglobulin receptor genes
published in Frontiers in Immunology.
Congratulations to Lenka Stejskal for giving the Best Oral
Presentation at the HCV2018,
the 25th International Symposium on Hepatitis C Virus and Related
Viruses in Dublin!
Several present and former members of the group have had a paper
about missense mutation haemophilia A accepted by
journal of the European Hematology Association.
Congratulations to Lenka Stejkal for having an oral presentation on
her research accepted by HCV2018 (the 25th International Symposium
on hepatitis C virus).
Three MSc Bioinformatics students have joined the group to work on
their Masters projects: Trupti Gore (plasmid fertility
inhibition), Georgina Toye (antibody binding motifs) and Ifigenia
Tsitsa (Pepscan epitope mapping data).
Adrian Shepherd is giving a lunchtime seminar on the group's
research (T-cell tolerance prediction, antibody
repertoire analytics, molecular dynamics) at the School of
Biosciences, University of Kent, Canterbury on the 27th.
The group has a "spotlight" paper published in Journal of
Virology with our
collaborators at NYU School of Medicine and Iowa State
— see the abstract
Pejvak Moghimi (BBSRC CASE studentship) has joined the group
to do a PhD on antibody repertoire analytics (in
collaboration with UCB).
Adrian Shepherd is giveng a talk — Antibody repertoire
analytics: deep sequencing meets “the evolution
within us” — at
a BIDA workshop
William Lees be presenting a poster about our antibody
repertoire sequencing work at
the SysIms: Systems
Biology of Adaptive Immunity conference in Ascona,
Switzerland, 14-17 May.
February 2017: Martin Rosellen has joined
the group to do a LIDo PhD rotation project modelling Factor
VIII interactions using Molecular Dynamics.
January 2017: The group has its first
December 2016: Congratulations to William
Lees and Jan Czarnecki for having chapters
repertoires analysis with NGS
pathway mining published in Bioinformatics Volume II:
Structure, Function, and Applications.
Guy Williamson (MRes Bioinformatics with Systems Biology) has
joined the research group to do a research project on
October 2016: There is
a BBSRC-funded PhD position
available in the group — a
collaboration with biopharma company UCB. It's a project
on antibody repertoires focusing on the visualisation and
analysis of NGS (Rep-seq) data. The application deadline
is 20th Jan. More information is
Lenka Stejskal (Wellcome Trust PhD Programme) has
joined the group to do a PhD on B-cell responses to
hepatitis C virus (in collaboration with Joe Grove at
William Lees has added more tools for antibody clonal
analysis (including ClusterStats
and Spectratype) to
William Lees has added clustering and germline analysis
Congratulations to Kevin Pentiah for successfully completing his
Congratulations to Anna Hernandez for having
accepted by Molecular & Cellular Proteomics.
June 2016: Elise Parey (Masters in Bioinformatics and Modelling, Pierre and Marie Curie
University, Paris) has joined the group to do a summer internship on antibody VH genes.
March 2016: Four MSc Bioinformatics students have joined the group to do their Masters projects:
Daniel Bugembe-Lule (HIV), Sandy MacPherson (chronic hepatitis B infections), Sam McGreig (fungal growth and
climate change) and Mark Warren (T-cell epitope immunodominance).
Congratulations to Michael Denyer for having a paper accepted
by PLOS ONE.
Adrian Shepherd was a plenary speaker and chaired the computational
biology session at VAAVV 2015, the Vaccines Against
Antigenically Variable Viruses Symposium, Ames, Iowa, US on
the 6th. William Lees presented an abstract and poster at the
same conference. Charles Bird, Frough Froghi and Jacob Househam (MRes Bioinformatics
with Systems Biology) have joined the group to do
computational immunology research projects.
October 2015: William Lees has added new functionality to our Phylogenetic Analysis
Tools: a tool for analysing IgBLAST reports; a tool for
extracting sequences and sequence fragments from IMGT and
IgBLAST reports; and expanded and improved documentation, now
available via GitHub. Arundhati Maitra and Lenka Stejskal have joined the group to do
Wellcome Trust PhD rotation projects.
William Lees has added the generation of WebLogo
sequence logos to the output from
Congratulations to William Lees for having a paper accepted by Journal
of Immunology Research.
Adrian Shepherd will be giving a talk at PHE (Public Health
England) Porton on the 23rd.
Adrian Shepherd gave a talk at the Pirbright Institute on
the 5th. Paul Buckley and Adam Shepherd (MSc Bioinformatics with Systems
Biology) have joined the group to do research projects on
T-cell responses to influenza A and antibody germline
Sukhuma Starkings (MSc Microbiology) has joined the
group to do a project on viral surface glycoproteins.
Tapasvi Modi has joined the group to do a PhD on anthrax
vaccines in collaboration with Public Health England.
Siobhan Titre-Johnson (MSc Health and Disease) has joined the
group to do a project on influenza B virus.
Anna Laddach and Zheli Tan (MRes Bioinformatics with Systems
Biology) have joined the group to do research projects on NGS
antibody repertoire sequencing.
Roxana Mironska has joined the group to do a Wellcome Trust PhD
Adrian Shepherd gave a talk at the Respiratory Viruses 2014
symposium in Oxford on the 8th.
Sebastiaan Klein has joined the group on an internship from the
University of Applied Sciences Leiden. Aaron Yi Long Lam (BSc
Biochemistry, UCL) has joined the group to do his third year
research project on heterologous immunity.
Congratulations to Kevin Pentiah for having a paper
accepted by Glycobiology.
Congratulations to Stuart Skelton for having a paper
accepted by the British Journal of
June 2014: Adrian Shepherd gave a talk at the Institute of Hepatology on the 4th of
March 2014: Ginny Devonshire and Paddy
MacMahon (MSc Bioinformatics with Systems Biology) join the
group to do their research projects. Our recent paper on
broad-spectrum antibodies against influenza A (Lees, Moss
& Shepherd, 2014) is featured on the Society for General
Microbiology blog, Microbe
Adrian Shepherd has joined the Programme Committee for SMBM
2014 (the 6th International Symposium on Semantic Mining in
January 2014: Rute Magalhaes and Paula
Luz Horne (MSc Microbiology students) join the group to do
their research projects. Claire Winship has joined the
group to do a postgraduate internship on influenza
Adrian Shepherd gave a talk on
computational virology at the
Center for Advanced Host Defense, Immunobiotics, and
Translational Comparative Medicine (CAHDIT), Iowa State
University on the 14th of the month. Michael Denyer (MRes
Bioinformatics with Systems Biology) joins the group to work
on T cell responses to influenza A.
Congratulations to William Lees for having a paper
accepted by Journal of General Virology.
September 2013: Congratulations to William Lees for
passing his PhD viva and giving a talk at the Influenza2013 conference
in Oxford. The following students have joined the group: Mary Bispham,
Naz Uzun and Charlie Watson to start their part-time PhDs on
herpesviruses, HBV and influenza A respectively; Jake Saklatvala (BSc
Biochemistry, UCL) to do his final year research project; and Sander
van Boom as an intern, part of his bioinformatics degree at the
University of Leiden, Netherlands.
August 2013: Adrian Shepherd has joined the Programm
Committee for LBM 2013 (the 5th International Symposium on Languages
in Biology and Medicine)
June 2013: Mike Doyle (BSc Chemical and Molecular
Biology) joins the group to work on his research and literature
May 2013: Richard Lee (MSc Bioinformatics with Systems Biology)
group to work on the immunogenicity of therapeutic proteins.
Lisa Byer, Anthony Folami and Duldip Sidhu (MSc Health and
Disease students) join the
group to work on their research projects.
Dr James Smith joins the
group to work on SysMIC.
Claire Haskins (MRes Bioinformatics with Systems
Biology) joins the group to work on the evolution of immune regulation. Adrian Shepherd gave a talk
on the stratification of haemophilia A patients at the
Centre for Systems and Synthetic Biology, Brunel
University on the 7th.
William Otterburn (BSc Biochemistry student at UCL)
group to do his third year research project on
Cangratulation to Simon Corrigan for having his
poster accepted for ECCB'12.
Congratulations to Jan for having a paper
based on his 1st-yr PhD
rotation project accepted by BMC
Oliver King (BSc Biochemistry student at UCL)
joins the group to do an internship in protein
April 2012: Sumona Mitra (MSc
Bioinformatics graduate from King's College London)
joins the group to do an internship in
immunoinformatics. Congratulations to Ganesh for
based on his 1st-yr PhD rotation project accepted
by Molecular Immunology.
March 2012: Alison Kakoschke, Nazmiye
Uzun and Shavin Fonseka (MSc Bioinformatics with
Systems Biology) join the group to do their research
projects. Adrian Shepherd has joined the Programme
Committee of the 5th International Symposium on
Semantic Mining in Biomedicine (SMBM 2012, Zurich, 3/4
Christian Search and Patience Tetteh (MSc Health and
students) join the group to do their
The SysMIC (Systems Training in Maths, Informatics and
Computational Biology) project has started. More
Johnathan Watkins joins the group to work on a joint
with Dr Anita Grigoriadis at
the Breakthrough Breast Cancer Research Unit, King's
Congratulations to group member Jan Czarnecki for
first prize for his presentation
at the ISMB 2011 Graduate Symposium!