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  • April 2020: MSc Bioinformatics students Sucharitha Balu, Kieran Drake, Kyvi Nguyen, Vuyelwa Nkomo and Ruchira Sachdeva have joined the group to do their projects on B-cell germline genes, T-cell receptors, and SARS-CoV-2.
  • March 2020: Adrian Shepherd is giving a talk about the group's computational immunology research at the Royal Veterinary College on the 4th.
  • February 2020: Congratulations to Lenka Stejkal and other group members for having a paper on the hepatitis C virus E2 glycoprotein published in PLOS Computational Biology.
  • January 2020: Sarah Griffiths joins the group to do an internship aimed at evaluating different antibody repertoire annotation tools.
  • November 2019: Adrian Shepherd is giving a talk on alloimmunity and our proteome scanning strategy at the Immunogenicity and Tolerance Seminar in Amsterdam on the 15th. Three members of the group are co-authors on a paper in Frontiers in Immunology abouta statistical package for analysing and comparing immune receptor repertoires called sumrep.
  • October 2019: Zainab Aziz and Trupti Gore join the group to do internships on MHC molecule binding signatures and HLA allele prediction from T-cell receptor sequences respectively.
  • September 2019: Congratulations to Dr William Lees for having two papers accepted in Nucleic Acids Research — one for our database OGRDB, and one for VDJbase, which we host and jointly develop with Gur Yaari's lab.
  • June 2019: Adrian Shepherd is giving a talk about antibody repertoire sequencing at the Antibody Engineering & Therapeutics Europe conference in Amsterdam on the 13th.
  • April 2019: MSc Bioinformatics students Esther Adebanjo, Sam Dougan, Diego, Miruna Serian and Nikita Sharma join the group to do their Masters projects.
  • March 2019: Congratulations to William Lees for having a paper on inferred allelic variants of immunoglobulin receptor genes published in Frontiers in Immunology.
  • October 2018: Congratulations to Lenka Stejskal for giving the Best Oral Presentation at the HCV2018, the 25th International Symposium on Hepatitis C Virus and Related Viruses in Dublin!
  • September 2018: Several present and former members of the group have had a paper about missense mutation haemophilia A accepted by Haematologica, the journal of the European Hematology Association.
  • June 2018: Congratulations to Lenka Stejkal for having an oral presentation on her research accepted by HCV2018 (the 25th International Symposium on hepatitis C virus).
  • March 2018: Three MSc Bioinformatics students have joined the group to work on their Masters projects: Trupti Gore (plasmid fertility inhibition), Georgina Toye (antibody binding motifs) and Ifigenia Tsitsa (Pepscan epitope mapping data). Adrian Shepherd is giving a lunchtime seminar on the group's haemophilia A research (T-cell tolerance prediction, antibody repertoire analytics, molecular dynamics) at the School of Biosciences, University of Kent, Canterbury on the 27th.
  • February 2018: The group has a "spotlight" paper published in Journal of Virology with our collaborators at NYU School of Medicine and Iowa State — see the abstract here.
  • October 2017: Pejvak Moghimi (BBSRC CASE studentship) has joined the group to do a PhD on antibody repertoire analytics (in collaboration with UCB).
  • June 2017: Adrian Shepherd is giveng a talk — Antibody repertoire analytics: deep sequencing meets “the evolution within us” — at a BIDA workshop on the 20th.
  • May 2017: William Lees be presenting a poster about our antibody repertoire sequencing work at the SysIms: Systems Biology of Adaptive Immunity conference in Ascona, Switzerland, 14-17 May.
  • February 2017: Martin Rosellen has joined the group to do a LIDo PhD rotation project modelling Factor VIII interactions using Molecular Dynamics.
  • January 2017: The group has its first publication in Frontiers in Immunology.
  • December 2016: Congratulations to William Lees and Jan Czarnecki for having chapters on antibody repertoires analysis with NGS and metabolic pathway mining published in Bioinformatics Volume II: Structure, Function, and Applications. Guy Williamson (MRes Bioinformatics with Systems Biology) has joined the research group to do a research project on antibody-antigen complexes.
  • October 2016: There is a BBSRC-funded PhD position available in the group — a collaboration with biopharma company UCB. It's a project on antibody repertoires focusing on the visualisation and analysis of NGS (Rep-seq) data. The application deadline is 20th Jan. More information is available here. Lenka Stejskal (Wellcome Trust PhD Programme) has joined the group to do a PhD on B-cell responses to hepatitis C virus (in collaboration with Joe Grove at UCL).
  • September 2016: William Lees has added more tools for antibody clonal analysis (including ClusterStats and Spectratype) to the TRIgS GitHub site.
  • July 2016: William Lees has added clustering and germline analysis tools to our Phylogenetic Analysis Tools.
    Congratulations to Kevin Pentiah for successfully completing his PhD.
    Congratulations to Anna Hernandez for having a paper accepted by Molecular & Cellular Proteomics.
  • June 2016: Elise Parey (Masters in Bioinformatics and Modelling, Pierre and Marie Curie University, Paris) has joined the group to do a summer internship on antibody VH genes.
  • March 2016: Four MSc Bioinformatics students have joined the group to do their Masters projects: Daniel Bugembe-Lule (HIV), Sandy MacPherson (chronic hepatitis B infections), Sam McGreig (fungal growth and climate change) and Mark Warren (T-cell epitope immunodominance).
  • February 2016: Congratulations to Michael Denyer for having a paper accepted by PLOS ONE.
  • November 2015: Adrian Shepherd was a plenary speaker and chaired the computational biology session at VAAVV 2015, the Vaccines Against Antigenically Variable Viruses Symposium, Ames, Iowa, US on the 6th. William Lees presented an abstract and poster at the same conference. Charles Bird, Frough Froghi and Jacob Househam (MRes Bioinformatics with Systems Biology) have joined the group to do computational immunology research projects.
  • October 2015: William Lees has added new functionality to our Phylogenetic Analysis Tools: a tool for analysing IgBLAST reports; a tool for extracting sequences and sequence fragments from IMGT and IgBLAST reports; and expanded and improved documentation, now available via GitHub. Arundhati Maitra and Lenka Stejskal have joined the group to do Wellcome Trust PhD rotation projects.
  • September 2015: William Lees has added the generation of WebLogo sequence logos to the output from our Phylogenetic Analysis Tools.
  • July 2015: Congratulations to William Lees for having a paper accepted by Journal of Immunology Research.
  • April 2015: Adrian Shepherd will be giving a talk at PHE (Public Health England) Porton on the 23rd.
  • March 2015: Adrian Shepherd gave a talk at the Pirbright Institute on the 5th. Paul Buckley and Adam Shepherd (MSc Bioinformatics with Systems Biology) have joined the group to do research projects on T-cell responses to influenza A and antibody germline polymorphisms.
  • February 2015: Sukhuma Starkings (MSc Microbiology) has joined the group to do a project on viral surface glycoproteins.
  • January 2015: Tapasvi Modi has joined the group to do a PhD on anthrax vaccines in collaboration with Public Health England. Siobhan Titre-Johnson (MSc Health and Disease) has joined the group to do a project on influenza B virus.
  • November 2014: Anna Laddach and Zheli Tan (MRes Bioinformatics with Systems Biology) have joined the group to do research projects on NGS antibody repertoire sequencing.
  • October 2014: Roxana Mironska has joined the group to do a Wellcome Trust PhD rotation project.
  • September 2014: Adrian Shepherd gave a talk at the Respiratory Viruses 2014 symposium in Oxford on the 8th. Sebastiaan Klein has joined the group on an internship from the University of Applied Sciences Leiden. Aaron Yi Long Lam (BSc Biochemistry, UCL) has joined the group to do his third year research project on heterologous immunity.
  • August 2014: Congratulations to Kevin Pentiah for having a paper accepted by Glycobiology.
  • July 2014: Congratulations to Stuart Skelton for having a paper accepted by the British Journal of Haematology.
  • June 2014: Adrian Shepherd gave a talk at the Institute of Hepatology on the 4th of the month.
  • March 2014: Ginny Devonshire and Paddy MacMahon (MSc Bioinformatics with Systems Biology) join the group to do their research projects. Our recent paper on broad-spectrum antibodies against influenza A (Lees, Moss & Shepherd, 2014) is featured on the Society for General Microbiology blog, Microbe Post, here.
  • February 2014: Adrian Shepherd has joined the Programme Committee for SMBM 2014 (the 6th International Symposium on Semantic Mining in Biomedicine)
  • January 2014: Rute Magalhaes and Paula Luz Horne (MSc Microbiology students) join the group to do their research projects. Claire Winship has joined the group to do a postgraduate internship on influenza pseudoviruses.
  • November 2013: Adrian Shepherd gave a talk on computational virology at the Center for Advanced Host Defense, Immunobiotics, and Translational Comparative Medicine (CAHDIT), Iowa State University on the 14th of the month. Michael Denyer (MRes Bioinformatics with Systems Biology) joins the group to work on T cell responses to influenza A.
  • October 2013: Congratulations to William Lees for having a paper accepted by Journal of General Virology.
  • September 2013: Congratulations to William Lees for passing his PhD viva and giving a talk at the Influenza2013 conference in Oxford. The following students have joined the group: Mary Bispham, Naz Uzun and Charlie Watson to start their part-time PhDs on herpesviruses, HBV and influenza A respectively; Jake Saklatvala (BSc Biochemistry, UCL) to do his final year research project; and Sander van Boom as an intern, part of his bioinformatics degree at the University of Leiden, Netherlands.
  • August 2013: Adrian Shepherd has joined the Programm Committee for LBM 2013 (the 5th International Symposium on Languages in Biology and Medicine)
  • June 2013: Mike Doyle (BSc Chemical and Molecular Biology) joins the group to work on his research and literature projects.
  • May 2013: Richard Lee (MSc Bioinformatics with Systems Biology) joins the group to work on the immunogenicity of therapeutic proteins.
  • January 2013: Lisa Byer, Anthony Folami and Duldip Sidhu (MSc Health and Disease students) join the group to work on their research projects.
  • December 2012: Dr James Smith joins the group to work on SysMIC.
  • November 2012: Claire Haskins (MRes Bioinformatics with Systems Biology) joins the group to work on the evolution of immune regulation. Adrian Shepherd gave a talk on the stratification of haemophilia A patients at the Centre for Systems and Synthetic Biology, Brunel University on the 7th.
  • September 2012: William Otterburn (BSc Biochemistry student at UCL) joins the group to do his third year research project on functional epitopes.
  • August 2012: Cangratulation to Simon Corrigan for having his poster accepted for ECCB'12.
  • July 2012: Congratulations to Jan for having a paper based on his 1st-yr PhD rotation project accepted by BMC Bioinformatics.
  • June 2012: Oliver King (BSc Biochemistry student at UCL) joins the group to do an internship in protein modelling.
  • April 2012: Sumona Mitra (MSc Bioinformatics graduate from King's College London) joins the group to do an internship in immunoinformatics. Congratulations to Ganesh for having a paper based on his 1st-yr PhD rotation project accepted by Molecular Immunology.
  • March 2012: Alison Kakoschke, Nazmiye Uzun and Shavin Fonseka (MSc Bioinformatics with Systems Biology) join the group to do their research projects. Adrian Shepherd has joined the Programme Committee of the 5th International Symposium on Semantic Mining in Biomedicine (SMBM 2012, Zurich, 3/4 September).
  • February 2012: Christian Search and Patience Tetteh (MSc Health and Disease students) join the group to do their research projects.
  • January 2012: The SysMIC (Systems Training in Maths, Informatics and Computational Biology) project has started. More information here.
  • November 2011: Johnathan Watkins joins the group to work on a joint project with Dr Anita Grigoriadis at the Breakthrough Breast Cancer Research Unit, King's College London.
  • July 2011: Congratulations to group member Jan Czarnecki for winning first prize for his presentation at the ISMB 2011 Graduate Symposium!